Metoclopramide, a drug approved in the U.S. for nausea, vomiting and heartburn poses no significant risks for the fetus according to a large cohort study published in the June 11 issue of the prestigious New England Journal of Medicine, “The Safety of Metoclopramide Use in the First Trimester of Pregnancy” (N Engl J Med 2009;360:24 June 11, 2009). According to the pediatrician and clinical pharmacologist, principal investigator Dr. Rafael Gorodischer, prof. supplement rating
Canadian Light Source (CLS) staff scientist Luca Quaroni and Dr. Alan Casson, Head of the Department of Surgery at the University of Saskatchewan (U of S) used the synchrotron’s infrared microscope to identify tissue afflicted with a condition known as Barrett’s Esophagus from chemical fingerprints associated with the disease, which can lead to esophageal cancer. The finding is published in the June, 2009 issue of the Royal Society of Chemistry journal, The Analyst. supplement rating
Adding AZD3355, a novel GABAB receptor agonist, to a proton pump inhibitor (PPI) in patients with Gastroesophageal Reflux Disease (GERD), resulted in a 35% reduction in the mean total number of reflux episodes 0-24 hours after dose, compared with placebo.[i] These data were presented at the Digestive Diseases Week annual meeting (DDW®, 30 May – 4 June, Chicago). supplement rating
Patients who have gastroesophageal reflux disease (GERD) for a prolonged period have an increased risk of developing Barrett’s esophagus, a pre-cancerous condition where the tissue lining the esophagus becomes damaged by stomach acid and transformed into something like the inside of the stomach. New research finds that radiofrequency ablation — an endoscopic procedure involving targeted thermal energy — was very successful at restoring the esophagus and reducing risk for cancer. supplement rating
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