Cephalon, Inc. (Nasdaq: CEPH) announced positive results from a phase two clinical trial of NUVIGIL(R) (armodafinil) Tablets [C-IV] as adjunctive therapy for treating major depressive disorder in adults with bipolar I disorder. An estimated two million American adults are affected by bipolar I disorder, which is characterized by fluctuations between extreme highs (manic) and lows (depressed) in mood. pharmaceutical distributor
Scientists in Switzerland are reporting an advance that could help tap the much-heralded potential of “quantum dots” – nanocrystals that glow when exposed to ultraviolet light – in the treatment of cancer and other diseases. They are publishing the first study showing that giving quantum dots an icing-like cap of certain sugars makes these nanoparticles accumulate in the liver but not other parts of the body. pharmaceutical distributor
Semafore Pharmaceuticals, Inc. announced that it has achieved proof of concept in its CRIMP (Control Resulting from Inhibiting Multiple Pathways) kinase platform by designing a small molecule that was demonstrated to inhibit members of both the PI3K (Phosphoinositide-3-kinase) pathway and the Ras-MAPK (Ras-mitogen activated protein kinase) pathway. Specifically, SF2626 has demonstrated the ability to inhibit both PI3K and MEK, the key component of the RAS/RAF/MEK/ERK pathway. pharmaceutical distributor
The pharmaceutical industry has incurred the wrath of many who complain about high health care costs, harmful side effects and dubious benefits of new medicines. The barrage of criticism is unfair, argues John LaMattina, a 30-year veteran and former president of Pfizer Global Research and Development, and author of the book DRUG TRUTHS: Dispelling the Myths About Pharma R & D. pharmaceutical distributor
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